Similar(60)
This could be because area-wide management of these pests has been effective enough to prevent high levels of damage in refugia [ 1, 2], because the results here which are based on a small-scale field trial may not scale up to larger refugia or because bivoltine dynamics limit the opportunities for damage-avoiding oviposition to a single generation per year [ 44].
We know that very complex processes of growth and development are occurring which create windows of opportunity for damage".
Proliferation is associated with increased levels of DNA synthesis, which in turn provides opportunities for DNA damage by mammary carcinogens and an increased probability of reproduction of unrepaired or misrepaired DNA damage to the progeny of the damaged cell [ 44].
As age increases, subjects accumulate more opportunities for DNA damage due to prolonged exposure to UV radiation and other carcinogens.
Estrogen may induce hormone mediated cell proliferation that can result in genetic alterations and greater opportunity for genetic damage [ 21, 63].
The TP53 gene encodes the protein p53, a transcriptional regulator that is activated in response to a wide range of cellular stresses, resulting either in a delay in cell cycle progression (providing an opportunity for DNA damage repair) and in some cases in senescence or in the initiation of programmed cell death (apoptosis) (for review see Vousden, 2006).
The grounds for further complaint, and thus the opportunities for inflicting mutual damage, are immense.
Here, even a few years away from a career caring for children can hugely damage opportunities for advancement and success.
This paper describes this alternative approach, and discusses opportunities for improved sustainability through damage-resistant seismic design and renewable materials.
First to his feet was former Tory education secretary Kenneth Clarke, who asked Greening to make sure that "this change does not damage the opportunities for pupils in other schools and does not distract priority from raising the standards of all schools for all pupils which has been the objective of this government".
We speculate that the accumulating hPTTG1-induced DNA damage provides opportunities for cancer cells to evade senescence.
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