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USE elastogram interpretation is also operator dependent for several reasons.
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Firstly CEUS remains an operator dependent imaging technique; for this reason the creation of a common semiautomated software for the image elaboration could increase the reproducibility and the homogeneity among different operators.
Various components of USE acquisition and interpretation are operator dependent including freehand compression for strain USE, selection of imaging planes through nodules, selection of representative elastograms, qualitative scoring of elastograms and placement of ROIs for (semi- quantitative measemi- quantitative
The technique is operator dependent with a steep learning curve for both the sonologist and cytopathologist[ 23 26 ].
Once heavily criticised for being too "operator dependent," several technical advances have dramatically improved the accuracy and reduced variability of SE.
For instance, ultrasound imaging is highly operator dependent and is not sensitive enough to detect liver tumors in patients with cirrhotic background.
Other noninvasive technologies such as thoracic bio-impedance for cardiac output determination are less operator dependent and can be applied in the ED.
Cryopreservation of SLN single-cell suspensions allows for simultaneous phenotypic multi-parameter analyses and minimizes operator dependent variability.
Ultrasound is operator dependent; measurements on ultrasound are subjective and they cannot be reproduced for independent review.
Ideally automated detection of the differentiation between cortex and medulla using a digital threshold for signal intensity would generate more reliable, less operator dependent and hence reproducible data.
33 57 86–88 Furthermore, the recent publication of validated international criteria specifically developed for colorectal polyps differentiation using NBI 7 holds promise for making endoscopic diagnosis more standardised and less operator dependent.
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