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All patients underwent standardized surgical resection for upper gastrointestinal cancer, with prophylactic cefuroxime and metronidazole at induction and two post- operative doses.
This is slightly below the standard post-operative dose of 10mg to 12mg, but the covert dose had to be increased to the full 12mg to surpass the effect of the placebo.Great stuff, but there is a second reason why prescribing placebos may fall foul of the AMA: overworked doctors use them to deal with troublesome patients.
To investigate the effectiveness of a single pre-operative dose of sublingual misoprostol on reducing blood loss in abdominal hysterectomies performed for symptomatic uterine leiomyomas.
To investigate whether a single pre-operative dose of 120 mg acetylsalicylic acid (ASA) decreased either (1) emboli rate, as detected by transcranial Doppler (TCD), during and early after carotid endarterectomy (CEA) and (2) clinical intra- and post-operative signs suggestive of embolism or increased bleeding tendency.
All patients received a single pre-operative dose of dicloxacillin.
A pre-operative dose of 1 g cefazolin was given intravenously and a post-operative dose was given 4 hours after completing the procedure.
The single dose (1D) group received a pre-operative dose of dexamethasone of 1 mg/kg.
In this randomized trial, we report the efficacy of a single peri-operative dose of ampicillin-sulbactam or cefuroxime as chemoprophylaxis in patients undergoing cesarean delivery.
In fact, the only dose that has been shown to be important in preventing post-operative infections is the pre-operative dose [ 7, 9, 10].
We recorded protocol deviations whenever a pre-, intra-, or post-operative dose was missed, given incorrectly, or supplemented with additional non-study antibiotics.
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CEO of Professional Science Editing for Scientists @ prosciediting.com