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Significantly, despite variation in sequence and locations of the FG repeats in Nups, the number of FGs and sequence environment within which the FGs are embedded appear to be better conserved, implying conservation of the gating mechanism, although the precise mechanisms by which this operates remain controversial [ 14,16].
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The specific mechanisms by which industry influence may operate remain unclear and are most likely varied.
The exact details of how future personalized therapeutic approaches will operate remain to be determined by the wider medical community.
They find clinical application as anti-epileptics and chemotherapeutic agents, but the pathways through which they operate remain unclear.
In the US, a few centralized IRBs (CIRBs) have been established, but how they do and could operate remain unclear.
With a few notable exceptions, the specific mechanisms through which environmental triggers operate remain largely uncharacterized to date.
Indeed, the interplay between the destructive and generative aspects of extinction and the very different time scales over which they appear to operate remain crucial but poorly understood components of the evolutionary process (Jablonski 2001).
Output at U.S. factories, mines and utilities eked out a small gain in August, although the pace at which industries operated remained slow, the Federal Reserve said in a report Monday.
The objective of the analysis presented in this paper is to identify key actors in the three consecutive health reform periods, their relative influence in the health policy process and the context in which they operated; remaining challenges are also defined.
Julie Gardner, a spokeswoman for Continental Express, said, "As long as others are allowed to operate during the curfew, we also have to operate to remain competitive".
A number still operate, and remain beyond the knowledge or control of the Afghan government.
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