Despite the risk of needle-track seeding, RFA is considered a curative treatment for small HCC lesions, and there is ongoing debate whether RFA could potentially be considered a first option for operable patients with very early stage HCC (BCLC stage 0) [75] 75].
Induction or neoadjuvant chemotherapy is an option in operable breast cancer where first-line breast-conserving surgery is not possible, in the absence of multifocal lesions, and where the patient would prefer breast conservation (option).
Neoadjuvant chemotherapy (NACT), initially an approach for locally advanced, inoperable tumours, has become an established treatment option for operable breast cancer (Goldhirsch et al, 2007; Kaufmann et al, 2012).
Until the recent incorporation of neoadjuvant chemotherapy as a standard treatment option for operable gastro-oesophageal tumours (Cunningham et al, 2006), fit patients routinely received surgery in our centre.
With recent incorporation of neoadjuvant chemotherapy as a standard treatment option for operable gastro-oesophageal tumours (Cunningham et al, 2006), we also established a second TMA of 103 gastric/gastro-oesophageal cancer cases exposed to preoperative platinum-based chemotherapy.
Originally used only in women with locally advanced inoperable breast cancer, PST can now be offered as a very good option for primary operable disease in patients who are candidates for adjuvant systemic chemotherapy, irrespective of the size of the tumor [ 1].
From a set of design options, Mr. Adams selected operable windows on four sides and sliding glass doors.
Pulmonary RFA is still in its infancy; acceptance of the procedure as an alternative treatment option for non-operable lung tumours is quite recent.
In conclusion, this new fractionated fixed dose administration of oral vinorelbine concomitantly with cisplatin and radiotherapy, following induction vinorelbine/cisplatin is feasible, and offers a well-tolerated (in terms of esophageal and hematological toxicities) therapeutic option, in non-operable IIIA-IIIB NSCLC.
