Sentence examples for opening of interaction from inspiring English sources
Such opening of interaction surfaces might increase 'premature' interactions of cargo proteins actually destined for AZ assembly, thus increase overall size of the cargo complexes by oligomerization between AZ proteins and, finally, promote premature capture and ultimately ectopic AZ-like assembly.
However, AIP binding may either facilitate an opening of this intramolecular interaction or stabilize the open conformation to alleviate CARMA1 activation and downstream signaling.
Thus, we can speculate that interactions between the gating loop and slide helix may promote channel opening, whereas interaction of the gating loop with the lower end of TM2 may promote the closed state.
We tested the association between opening of InsP3R and the CIB1-ASK1 interaction under IRE1 α-KD conditions and found that IRE1 α KD enhanced the CIB1-ASK1 interaction but reduced the CIB1-InsP3R interaction, which in turn resulted in increased Ca2+ release from InsP3R.
Cyclosporine A, however, prevents opening of mPTP by inhibition of its interaction with cyclophilin D [ 3, 39].
As suggested, this interaction could mediate opening of the hinge dimer during cohesin loading onto DNA (Gruber et al, 2006).
1 4 ORAis is the principal SOCE channel in the pancreatic acinar cell, the opening of which is coordinated by stromal interaction molecule (STIM 1 and STIM2, after decreases in endoplasmic reticulum calcium store concentrations.
Whereas BCL10-MALT1 associatoon thethe CARD opens up the N-terminus of CARMA1, AIP interacts with the PDZ-SH3 and may thereby facilitate loss of C-terminal GUK-SH3 interaction to support opening of the C-terminal MAGUK region and downstream signaling.
These openings could be the first cracks in a dam that holds back a flood of interaction.
Possible explanations for such anomalies are discussed in terms of many-body interactions and the opening of a gap.
The opening of the Suez Canal altered British interactions with the colonies of the British Empire as the dynamics of transportation, trade and communication had now changed drastically.
