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The phrase "open up about" is correct and can be used in written English.
You can use it when you want to express that you are willing to share something about yourself or a situation, or when you want someone else to do so. Example sentence: I was nervous to open up about my problems, but my therapist was very understanding.
Exact(59)
Open up about how you felt becoming a member of this new family.
Why don't more employees open up about their disabilities?
He added: "I want to open up about this.
If they open up about their (different) experiences they risk being misunderstood.
Another aspect of it that is deeply personal is that I really open up about me.
The Cheneys are not ones to open up about their personal lives.
They urged Aron to open up about his relationship with Kellner.
This was the first time Madeleine had heard Leonard open up about his work.
In addition to singing a song or two, they are expected to open up about themselves.
As a security researcher, I have only recently seen organizations open up about cyberattacks.
Nancy has agreed to open up about her job for the Guardian's series A Day's Work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com