Sentence examples for open spontaneously from inspiring English sources

If properly designed and applied, such self-regulating, ultra-adaptable, and stable hetero-aggregates can open spontaneously and carry drugs through ≤ 109 cm− 2 cutaneous pores in the primary skin barrier and minimise cutaneous drug clearance; this permits deep/targeted deposition and prolonged action of the carrier-transported drugs.

While in the KNO3 solutions, NO3 − binds to the SMC with the lowest affinity, therefore the channels could open spontaneously without pressure applied.

Consistently, electrophysiological studies of single channel with the YnaIΔ2−63 mutant clearly show that the channel can open spontaneously in KCl solutions without any external pressure (Fig. S6).

Indeed, in KF solutions, relatively high pressure is required to obtain detectable currents of the YnaI channel, while in KNO3 solutions, the YnaI channel could open spontaneously with much higher conductance even in the absence of any pressure (Fig. 4B).

In addition, mutant YanIM158A could open spontaneously without applied any pressure with almost the same ion selectivity in above three different solutions, which implies that selectivities influenced by the anions almost vanish, further highlights the important role of SMC element in ion selectivity (Fig. 4C and Table S2).

Previous studies demonstrated that the TM1 and TM2 may be responsible for gating the channel, and truncation of these two helixes would induce the channel to open spontaneously and present the typical gain-of-function behaviours when expressed in the living cells (Bottcher et al., 2015).

Apparently, the YnaIΔ2−63 mutant also opens spontaneously in KNO3 solutions.

In KCl and KNO3, YnaIΔ2−63 opened spontaneously without pressure applied (n = 5, n = 4, respectively).

YnaIM158A opened spontaneously without pressure applied to the pipette in asymmetric KCl, KF, and KNO3 solutions.

In KNO3, YnaI channel opened spontaneously without pressure applied (n = 4).

The Glasgow Coma Scale has three subscales, measuring the best motor response (ranging from "no motor response" to "obeys commands"), the best eye response (ranging from "no eye opening" to "eyes opening spontaneously") and the best verbal response (ranging from "no verbal response" to "fully oriented").