Sentence examples for open new targets from inspiring English sources

These results open new targets for understanding migraine pathophysiology.

The conversion of CD4+CD25− T cells into iTreg may be an important mechanism in the dynamic regulation of immune responses in vivo and the elucidation of its mechanisms may open new targets for therapeutic intervention.

For this reason, we hypothesized that a better characterization of the ECM protein expression in IPF lungs could provide relevant information to understand the progression of this lethal interstitial lung disease and to open new targets for therapeutic approaches.

While it is legitimate to focus on prototypic illness, as this represents the majority of cases and thus the bulk of disease burden, understanding the rarer AD subtypes and the influence of common comorbidities may open new targets for therapy and better allow the tailoring of existing ones - personalized medicine.

This sector also has the freedom to develop new drug discovery paradigms, seeking to change the well-trodden paths and methods of drug discovery to open up new target classes, new mechanisms of action, new cell models and, perhaps, one day addressing the ultimate goal of strategic polypharmacology [37].

As an alternative, nanotechnologies open new perspectives to target tumours.

Taken together, these findings have suggested that metabolic differences of various cancer cells types may open new ways of target identification towards more effective anti-cancer drugs.

These findings will open new avenues to target host cellular factors using RNAi and anti-miRNA technologies to combat HIV-1.

Importantly, the observed differences in the epigenetic code and transcriptional regulation in P. falciparum and its host will open new avenues for targeting the epigenetic machinery for drug development in malaria as well as other related parasites in future.

With the recent availability of the apple genome [ 60] and the impending release of the tomato genome, these NGST will certainly open new possibilities to target gene expression with high fidelity such as the repertoire of candidate ripening and evolutionarily conserved fruit genes that can be further expanded between tomato and apple and extended to additional important fruit crop species.

This identification of protein-protein interaction potentially opens new therapeutic targets to reduce the recurrence of DC.