Exact(9)
Although there are large differences in the leaflet deformations during diastole, the differences in the open configurations of the valve models are relatively small, and nearly identical hemodynamics are obtained in all cases considered.
First, the boundary of these plates must be designed such that they form an enclosure without any gaps or overlaps in both closed and open configurations, and the plates do not interfere with each other during deployment.
The work includes validation against experiments conducted in a variety of configurations including: (1) closed pipes with obstacles; (2) other congested lab-scale geometries; (3) medium to large-scale 3-D obstacle configurations; and (4) large-scale geometries where DDT occurred upon flame propagation from confined to more open configurations.
Together with our own findings, these results suggest that intersubunit interactions powerfully influence the activity and substrate selectivity of IDE, possibly by influencing the transitions between the closed and open configurations of each subunit.
In terms of the differences in Ki values, we speculate that larger substrates may be more capable than smaller ones of effecting the transition between the closed and open configurations, resulting in an increased off rate for the inhibitor.
L929 fibroblasts, which express low levels of p110δ mRNA and protein, were treated with 5'-azacytidine or trichostatin A, agents known to cause DNA (hemi-) demethylation and histone hyperacetylation, respectively, creating open configurations of genomic DNA to allow binding of TFs.
Similar(51)
Good ATMOSPHERE -- Cheerful, compact dining room with banquettes, yellow walls, open configuration and wood floors.
"It would be the highest-powered open configuration on the market," she said.
The open configuration has become a symbol of Mr. Bloomberg's management style in the corporate world.
Active genes are found in parts of the DNA where the chromatin has an "open" configuration, in which regulatory proteins are able to gain access to the DNA.
The addition of Teflon in an open configuration hinders the reaction due to a loss of liberated gas.
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