Sentence examples for open and active from inspiring English sources

In inactive conformation, Asp 835 interacts with Ser 838 to stabilize the activation loop while it interacts with Gln 667 to stabilize the activation loop in open and active state, a similar interaction has been observed for the stabilization of ABL kinase in active conformation.

However, on the basis of their propensity to induce an open and active SFK global conformation, these inhibitors are most likely selective for activated SFKs over their autoinhibited forms.

Given the lack of direct interaction of SAR302503 with resistant variants F691L and D835F/Y, our model suggests that these mutations would destabilize the open and active conformation rather than inactivating the kinase, therefore having sufficient catalytic activity to support cellular transformation.

"As long as Indian Point remains open and active, we continue to layer on more spent fuel".

"In my view the MPS needs to be more open and active in responding to responsible requests for information to improve its accountability to the public.

The recall does not extend to BirdBrain products, but a commission spokesman said its investigation into other companies and burn cases was "open and active".

The enhancer-associated marks are generally associated with open chromatin and active enhancers, which suggests that gain and loss clusters correspond to activation and repression, respectively.

Yes, they too had bought Leather's original line and so no wonder so many open, tolerant and active people of faith felt excluded in their efforts to build a bigger society.

It begins with open communication and active listening and focusing on commonalities that unite instead of differences that divide.

High TF peaks both had a higher degree of overlap between cell types and were more associated with open chromatin and active transcription, compared to low peaks.

Interestingly, cells mutant for scny have elevated ub-H2B and H3K4me3 signals, which probably leads to more open chromatin and active transcription of Notch target genes [ 62].