France and China, which had both previously had chemical-weapons programmes, said they destroyed their weapons shortly before signing the convention (those claims are subject to verification by OPCW inspectors).
She urged countries to contribute to an OPCW trust fund to pay the bill.
But Michael Luhan of the OPCW says that while there is no definition for destruction of such structures in the Chemical Weapons Convention (CWC), in OPCW "common law" it has come to mean "taken down to the foundations".
The mission – which has already seen OPCW inspectors come under sniper fire – was agreed as a means to avoid US-led militactiontion against Syria following a gas attack blamed on forces loyal to Bashar al-Assad in August which killed more than 1,400 people.
The Organisation for the Prohibition of Chemical Weapons (OPCW) has become the surprise choice for this year's Nobel peace prize, a decision the Oslo committee said recognised both its current, hazardous mission to destroy Syria's chemical weapons stocks and 16 years of wider global efforts.
When news of its win leaked there was initial scepticism, with some Middle East analysts warning it was premature to honour the OPCW just a matter of weeks into its mission to assess and destroy Syria's chemical weapons stocks.
In a echo of the impossibility this week of tracking down the winners of the prizes for physics and literature, Peter Higgs and Alice Monro, the Nobel committee tweeted that it had been unable to immediately speak to the OPCW to formally let it know of the win.
By means of the present award to the OPCW, the committee is seeking to contribute to the elimination of chemical weapons".
The OPCW, which has 500 staff, is the 25th institution among the 94 winners in the prize's history, and the second in succession, after the controversial choice of the EU in 2012.
The work of the OPCW, which has 189 member states, had "defined the use of chemical weapons as a taboo under international law", the committee said, adding that events in Syria had "underlined the need to enhance the efforts to do away with such weapons".
The OPCW was set up to implement the 1992 global chemical weapons convention.
