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To this end, we isolated OPC from the corpus callosum of GFAP-Cre Lgl1 cKO and GFAP-Cre Lgl1 WT control mice and cultured them under OL differentiation conditions in vitro34 and stained cells for NG2 and O4.
A series of six mixing proportions with a change of SSRS-cement ratio replacing ordinary Portland cement (OPC) from 0%to50%0% (increment 10%) were developed for experimental work.
However, as the replacement ratio of red mud becomes higher, there is no big change in the result in AAS, from 0.94 to 0.93 ml/g, while it is increasing in OPC, from 0.70 to 0.93 ml/g.
For replacing high volume of OPC from concrete ternary blend cement system is used where OPC is replaced by two different mineral admixtures one slow reactive mineral admixture like fly ash, blast furnace slag, etc. and other highly reactive mineral admixture like silica fume, metakaolin, etc. Fly ash and silica fume are the most commonly used two mineral admixtures.
In contrast, molecules able to promote proliferation, survival and maturation of rodent OPC from NSCs [34] are not similarly effective on hNSCs, pointing to inter-species differences in growth factor responsiveness [2], [35], [36].
Thus, additional studies aimed to define factors able to promote the enrichment and expansion of OPC from immature hNSCs are needed in the perspective of developing clinically applicable therapeutic strategies.
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These studies utilized either OPCs from P7 rat brains or human embryonic stem cell (hESC) derived OPC lineages.
We propose that aTf promotes OPC maturation and myelin recovery in the H/I CC by decreasing iron-mediated toxicity and inducing new OPCs from the SVZ.
However, the derivation of engraftable OPCs from human pluripotent stem cells has proven difficult and primary OPCs are not readily available.
The different cements studied were – two Portland pozzolana cements (PPCs) and their corresponding ordinary Portland cements (OPCs) from the same cement plant, and two blast furnace slag cements (BFSCs) along with the corresponding OPCs from the same factory.
This was distinct from what had been previously reported for neural stem cells34 or OPCs from mutants of other epigenomic regulators45.
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