Exact(21)
The softening was found to be only in the onset stage, without flow localization.
To deeply apprehend the pH-triggered hydrophobic drug release behavior, a semi-empirical equation (1) established by Siepmann and Peppas [46] is considered to analyze the drug release mechanism from the micelles by fitting these kinetic data for the onset stage of release [42, 47].
Though we observed a slight but significant reduction in the percentage of activated microglia and astrocytes at onset stage, neither survival nor motor performance of double transgenic mice differ from those of single transgenic ALS mice (Figure 4 5).
As shown in Figure 6, we observed a slight, but statistically significant, reduction of both CD11b and GFAP positive cells at the onset stage in double transgenic mice with respect to SOD1G93A mice.
Using an antibody that specifically recognizes an epitope overlapping the nuclear localization signal of the p65 subunit and, thus, selectively binding to the activated form of p65 (indicated as p65*), we evaluated the activation of NF-κB in single and double transgenic mice at the onset stage by Western blot.
Onset of breast and pubic hair development were coded separately as: "no onset" (Stage 1) or "onset" (Stage 2 or above).
Similar(39)
Patients with IgG4-RD respond beneficially to glucocorticoid therapy especially when given at early onset stages.
(a, c) Interseismic [70 and 50 years before the onset of a megathrust earthquake with the (a, b) SCM and (c, d) WCM, respectively] and (b, d) preseismic (10 years before the onset) stages.
(a, b) Same as Figure 4 for SCM in a full elastic medium (SCMF, without free surface conditions) in the (a) interseismic (40 years before the onset) and (b) preseismic (10 years before the onset) stages.
While typical surface analysis using the pin-on-disk apparatus is done ex situ, after wear took place, our experimental setup is designed to detect the minute changes suffered by the surface of the disk due to mechanical contact with the pin, showing the onset stages of wear during the initial transient, in real time.
In the early onset stages of Post Traumatic Stress Disorder (PTSD), flashbacks were a common occurrence in my daily life.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com