Your English writing platform
Discover LudwigExact(9)
The onset of side effects on the CNS occurred with a mean dosage of 600 mg for CBZ and 1200 mg for OXC.
Clinically, target occupancy can be used to unequivocally confirm "drug-on-target" (proof of mechanism), (Morgan et al. 2012) guide clinical dose selections, and enable data-driven clinical "Go/No Go" decisions depending on whether the onset of side effects occurs prior to or after desired target occupancy range for efficacy (Wong et al. 2009).
(P7, 52 yrs) The onset of side effects was usually unpredictable.
This apparent discrepancy may be explained by an earlier onset of side effects in elderly patients.
There is a scarcity of data in the literature comparing the onset of side effects between different embolizing agents.
The onset of side effects occurred with mean dosages of 600 mg for CBZ and 1200 mg for OXC.
Similar(51)
Several groups noticed another side effect, a general decrease in animal robustness, when treatment with rapamycin was started in very young mice [ 1, 8]; this underscores the importance of mTOR pathway activity during development and points out to the significance of another variable, the onset of treatment, in diminishing of side effects.
While antidepressant pharmacotherapy is an effective treatment of depression, it is still hampered by the slow onset of appreciable clinical improvement and a series of side effects.
Since then innumerable studies have shown better avoidance of side effects, reduction in medication load, faster onset of anesthesia, longer duration of blocks, and improved quality of blocks [5].
Treatment attributes included onset of effect, black box medication warning, improvement in oppositionality, clinician- and teacher-reported improvements in ADHD symptoms and a range of side effects.
The onset of anaemia during early infancy and the prolonged duration of steroid therapy make DBA unique with respect to the risk of side effects (Table V).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com