Laryngeal aerodynamic measurements were obtained for one patient before and after onset of paralysis using the Aerophone II (Kay Elemetrics).
In mice whose immune systems had been "trained" to attack myelin, which typically results in paralysis, A-beta injections delivered before the onset of symptoms prevented or delayed the onset of paralysis.
We found that TGF-beta1 synthesis in glial cells and TGF-beta-induced signaling in the CNS were activated several days before the onset of paralysis in mice with autoimmune encephalomyelitis.
By adjusting kS, the new model simulated the rapid decline in NMJ function (kS⩾0.01), the less rapid onset of paralysis in mice (i.m. injections; kS=0.001), and the slow development of the clinically related, therapeutic effects of BoNT/A (kS<0.001).
We tested the hypothesis that mathematical models having a minimal number of reactions can simulate published data concerning the onset of paralysis induced by botulinum neurotoxin serotype A (BoNT/A) at the isolated mouse neuromuscular junction (NMJ) and in other systems.
In ICU patients, a change in pharmacokinetics of cisatracurium may explain slower onset of paralysis and the need to administer larger doses.
We found that the best studied CaP60A mutant, the conditional paralytic mutant CaP60A kum170), develops marked bradycardia and chamber enlargement that is closely linked to the onset of paralysis and dependent on extra cardiac CaP60A.
Falls that resulted from a violent blow, loss of consciousness, sudden onset of paralysis as in a stroke, or an epileptic seizure were excluded from the final data set (Gibson et al. 1987).
Our previous study showed that Ot B delayed aging and aging-related disorders [11], we were wondering if the delayed onset of paralysis was the result of an anti-aging effect, rather than a reduction in toxicity.
These symptoms were preceded by a sudden onset of paralysis below the waistline without loss of bowel or bladder control, which occurred during the surgical placement of a neurostimulator.
Factors that increase the risk of polio infection or affect the severity of the disease include immune deficiency, malnutrition, physical activity immediately following the onset of paralysis, skeletal muscle injury due to injection of vaccines or therapeutic agents, and pregnancy.
