'onset of effect' is a valid phrase for written English.
It refers to something beginning to take effect or become noticeable. For example, "After a few weeks, the patient began to experience the onset of effect from the medication."
We conclude that aminohexane bisphosphonate is an effective agent in the treatment of tumour-induced hypercalcaemia, with rapid onset of effect and low toxicity.
Results: Onset of effect was within 72 hours.
Efficacy evaluations were performed at weekly intervals from baseline (randomization) to week 8. Changes in QIDS-SR-16 score at day 1 and MADRS score at day 3 were also measured to assess onset of effect.
The agents had to be added to an existing antidepressant regime with the aim of achieving an improved clinical response to an ongoing antidepressant treatment (augmentation) or an earlier onset of effect when starting antidepressant and augmentation agent simultaneously (acceleration).
Intravenous fentanyl achieves a similar degree of analgesia and a more rapid onset of effect without the need for epidural catheterization.
The reason for the early onset of effect and the delayed of onset of maximum effect could not be explained with the prophylactic properties of these drugs.
Although these findings were also noted in other studies [18, 22, 29], the onset of effect was reported in the 4-week period which was not significant.
Because of the rapid onset of effect with rivaroxaban, and in contrast to VKAs, there is no need for LMWH bridging.
The time of onset of effect of DFMO on the synthesis of nucleic acids and proteins was the same as that reported for depletion of polyamines by this treatment.
Unfortunately, data on onset of effect from the procedure was not available for all patients, therefore we cannot comment on time of therapeutic response, even though past studies have shown this to be quite rapid [11].
