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At MV onset (Day 0) and on Days 3, 7 and 10, until death or discharge, whichever occurred first, we recorded: (1) MV-related variables.
To investigate whether the levels of anti-CII antibodies were more critical at the onset of the disease we compared the total anti-CII serum levels at 3 days before the onset day of each animal that developed disease with the levels in those that remained healthy; we found a more pronounced difference (P = 0.0002).
The mice were treated intraperitoneally on the day of disease onset (day 1) and then on days 4 and 7 of disease with RB200 at the indicated doses.
The mean onset day of NP after MV was 4.2 ± 3.9 days.
We observed a possible influence on disease onset in COMP-deficient mice, with the mean onset day in COMP-deficient mice of 5.1 ± 3.35 days compared with 6.85 ± 3.4 days in control mice.
Three early time points (3, 6, and 10 days post-immunization [p.i.]), the time point of expected onset (day 15 p.i ., the time point for expected maximal clinical severity of arthritis (day 21 p.i ., the time point for transition to a chronic phase of disease (day 28 p.i ., and a late time point (day 38 p.i). were selected, and four animals per time point were sacrificed.
Similar(16)
During both surveys, the onset (day-of-year) of spring phenological stages were recorded using a 3-day monitoring interval and that of autumn stages with a 4-day interval.
Late-onset (day 7) tumors from CLP-operated mice displayed increased proportions of F4/80High.
The probability of person j being infectious on day t is derived from the symptom-onset day of person j and the distribution of the infectious period.
We recorded the day of onset, days of sustained IAH, surgical abdominal decompression, and resolution.
The Oximetry Score was able to differentiate exacerbation onset from day-to-day symptom variation with reasonable sensitivity and specificity.
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