Sentence examples for onset and attenuated from inspiring English sources

Importantly, passive immunization through administration of anti-KLK6 antibodies or active immunization through administration of recombinant rat Klk6, to induce the production of anti-KLK6 antibodies, delayed significantly the onset and attenuated the symptoms of experimental autoimmune encephalomyelitis (EAE), the mouse model for multiple sclerosis [25].

The inhibition of Tie2 delayed the onset and attenuated the severity of arthritis [ 16, 35].

Acute starvation, which is able to prevent increases in serum leptin, delayed EAE onset and attenuated clinical symptoms [ 42].

Genetic deletion of IFN-γ in CD25KO mice did not abolish development of autoimmunity; rather, it delayed its onset and attenuated the severity.

Here we demonstrate that pre-symptomatic antisense treatment targeted at inhibition of AChE expression improved survival with a trend towards delay of disease onset and attenuated loss of motor neurons in Tg-mice.

Progesterone administered prior to EAE immunization delayed onset and attenuates progression of neurological deficits [ 45].

We then investigated the mechanisms leading to the delayed onset of EAE and attenuated optic neuritis in Olig1−/− mice.

IL-17 single-deficiency significantly delayed the onset of diabetes and attenuated the severity of insulitis, but the cumulative incidence of diabetes until 50 weeks of age in IL-17 deficient mice was similar to that in wild-type (wt) mice.

At the most effective dose tested (2 mg/kg daily), diacerein inhibited the onset of arthritis in 28% and attenuated the progression of arthritis in 35% of the Tg197 mice.

In experimentally infected mice, the variant showed delayed onset of symptoms, a reduced viral load and attenuated lethality compared with the wild-type.

New onset of ultrasound-confirmed ascites and/or hepatomegaly and attenuated or reversed hepatic venous flow by ultrasound are more specific criteria, whereas gall bladder wall thickening despite being non-specific may be helpful for SOS/VOD diagnosis.