Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
Active securin binds to and inhibits separase activity, whereas degradation of securin releases separase to cleave centromeric cohesion at anaphase onset – a process dependent on APC-Cdc20 activation (Nasmyth, 1999; Nasmyth et al, 2000).
Similar(59)
Our data raise the possibility that the presence of OPN heralds the onset of a process that may ultimately lead to irreversible tissue damage.
Because most, if not all, cohesion is created during DNA replication, separase must remain inactive from S phase until the onset of anaphase, a process mediated by an inhibitory chaperone called securin and phosphorylation by cyclin B/Cdk1 [ 7].
PINK1 and Parkin are often found mutated in Parkinson patients and they are suspected pathological causes of early onset of Parkinson's disease, a process involving their regulatory role in mitophagy (Deas et al., 2011).
Forecasting its onset (as a specific event) should be separated from forecasting its behavior and impacts (as a process) once the onset has been assured.
These results suggest that an initial onset estimation process is indeed beneficial for lowering the manual annotation since such figures depict that half of the total number of onsets are properly handled by the autonomous detection system.
These results also show the clear advantage of adaptive threshold methods in the onset selection process when compared to a global initial value.
Therefore, genetic models of PD are highly desirable because they produce a delayed onset and a neurodegenerative process that probably mimics human PD better than neurotoxic models.
Diagnosis of ALI and ARDS required an acute onset of the process, bilateral infiltrates on a chest radiograph, no evidence of left atrial hypertension, and OSI > 6.5 (ALI) or > 7.8 (ARDS).
This would also mean that trabecular bone adaptation could be modeled as a system responding to an input signal at the onset of the process in a predefined manner, without feedback from the outputs.
On stop cue trials, a response is suppressed by the onset of a braking process that directly inhibits the execution process, preventing it from reaching the action threshold.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com