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Although elderly patients have not been excluded from randomised phase III trials evaluating the activity of second-line chemotherapy (Shepherd et al, 2000; Hanna et al, 2003), only very selected patients with good performance status are candidates to salvage chemotherapy in everyday clinical practice.
Although pelvic exenteration plays a definitive role in the management of recurrent cervical carcinoma, its impact in terms of the proportion of cervical cancer patients who benefit from such radical procedure has remained unchanged because it continues to be indicated in only very selected patients with small central pelvic recurrences.
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You and I can't buy into these companies; only very select institutions and well-connected individuals can.
It is therefore important to use these operations only in very selected groups of patient.
It is also appropriate to consider allograft and artificial ligaments only in very selected cases, discouraging widespread use, given the potential risks and paucity of well-performed, well-designed clinical studies.
Importantly, however, NR2F6 appears to alter the transcription levels of only a very selected subset of genes rather than promoting large-scale changes in gene expression.
The consequence, however, is a product of low specific activity and therefore used only in very selected cases, for example, with I-MIBG.
This dialysis technique is suitable only to very selected and motivated patients, who also follow a very low protein diet (0.3 0.4 g/kg/ideal body weight with keto-analogue supplements) [ 97, 98].
Furthermore, the inability to perform a bypass graft and the significant endoscopic skills required can be considered as other important drawbacks, making the ventral corridor indicated only in very selected cases.
However, this only reflects the very selected nature of our cohort, as the majority of patients were still alive within 2 years after their baseline fracture.
The Universe does form elements during the hot Big Bang, but only a very select few.
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CEO of Professional Science Editing for Scientists @ prosciediting.com