The genetic complexity of late-onset AD is underscored by the detection of only one consistent susceptibility factor; APOE ε4 (34).
This is in keeping with the prevailing view that LHON is a multifactorial disease, and the visual failure is likely due to a complex interaction between genetic and environmental factors, with smoking as only one of the susceptibility factors.
Additionally, of the isolates tested for antimicrobial susceptibility, only one isolate was intermediately resistant to tetracycline, a marker for susceptibility to doxycycline, the most commonly used antibiotic for treatment of cholera in Haiti.
In this case, the level of a standard would depend on only one variable, the NOAEL, instead of three: the NOAEL, the cohort susceptibility, and the disease definition.
Of note, there was only one isolate with non-susceptibility to ertapenem (MIC = 1 mg/L).
On the other hand, if the isolates showed similar susceptibility pattern, only one isolate was considered for further analysis.
In case multiple identical microorganisms with identical antibiotic susceptibility were identified on the same day in the same patient, only one microorganism was included in the susceptibility analysis.
Here we implicate neural pathways (e.g. axon guidance and long-term potentiation) in susceptibility to MS. Only one other article has reported a neural gene in MS susceptibility to date (32).
DEC had broadly preserved quinolone susceptibility, with only one EPEC isolate out of 120 DEC noted to be resistant to ciprofloxacin.
In another study conducted in Peru, only one Brucella isolate demonstrated reduced susceptibility to rifampin (1.0 μg/ml) [ 15].
