Only one reviewed study parametrised mortality by age, gender, and severity; others focused only on severity.
Other studies that examined apoptosis of circulating neutrophils from septic patients assessed only one level of severity of sepsis (for example, only severe sepsis [ 30- 32] or MODS [ 35]).
If participants had experienced only one level of severity during their most recent attack, they did not complete the EQ-5D for other levels of severity.
Pain is likely to be only one of several factors that contribute to patients' perceptions of OA severity, and while experiencing pain in the past month was included as a covariate, pain severity was not.
Of the 28 items from the 14 symptoms evaluated, the ICC for 16 items (57.1%) exceeded 0.6, and only one item (vomiting, severity) had an ICC of less than 0.4.
Therefore, the maximum number of EQ-5D administrations per participant was four (mild pain, moderate pain, severe pain, and current health [without migraine]), and the minimum number of EQ-5D administrations was two (only one level of severity experienced and current health [without migraine]).
Other studies have been based on only one symptom dimension, usually intensity or severity [ 12, 13].
Since there is only one child with severe disease, only two disease severity groups are compared (mild disease, n = 88; and moderate/severe disease, n = 24).
Identification of biases is possible only in an evidence synthesis framework, through the "triangulation" of multiple data sources: each source on its own provides a (potentially biased) view of only one aspect of the severity of an epidemic.
Only one study reported the severity of the MEs in detail, but was a retrospective study [ 21].
