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Such a loss will not only occur upon the desired recombination event but can also be simply caused by mutations that disrupt the function of the selectable marker.
Thus, our data indicate that the interaction between Ltv1, Rps3 and Enp1 might only occur upon phosphorylation of one or more of these proteins, as suggested previously [15].
This point needs some clarification in the Discussion: first these two alternative forms only occur upon the additional F34M mutation.
Successive ossification that will form the hard (primary) palate will only occur upon successful completion of the fusion process.
The covalent anchoring of the FAD cofactor is an autocatalytic process and will only occur upon correct folding of the polypeptide chain.
Our findings indicate that PanIN formation can only occur upon loss of epithelial Notch inhibition, thus supporting an essential role of this signaling pathway during pancreatic carcinogenesis.
Similar(53)
In contrast, glucose/THCPSi NPs, sodium nitrite/THCPSi NPs, PBS, and sodium nitrite solution controls showed no NO release (Additional file 1: Figure S2), demonstrating that the NO release indeed only occurs upon nitrite reduction.
Site-specific recombination only occurs upon administration of the drug tamoxifen (TAM) or its active metabolite, 4-hydroxy-tamoxifen (4-OHT).
Our data indicate that TDP-43 can associate with TIA-1, a primary SG protein, however association only occurs upon over-expressing TDP-43.
LTP of the synaptic component only occurs upon temporal proximity between stimulation via the entorhinal input and increased dentate spiking activity.
The transconjugants appeared blue on LB-agar plates supplemented with X-gal (5-bromo-4-chloro-3-indolyl-beta-D-galactopyranoside), whereas the PA14::cupD1-lacZ strain carrying the empty vector remained white, indicating that expression of the cupD1-lacZ fusion only occurred upon RcsB overproduction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com