Small but insignificant changes in MMAE or MME were seen in CNL patients.
miR-142 deficiency results in increased MkP numbers and only modest, insignificant, changes in PreMegEs.
In spite of considerable divergence in sequence, only functionally insignificant changes constitute the sequence differences in SAP30L between these two clades.
However, in the present study, we only observed insignificant changes in local activation time whether in the presence of reduced [K+]o alone or in combination with any of the pharmacological agents used (data not shown).
Local activation time is the time measured from the point of electrical stimulus to the maximal amplitude of the AP repolarization time is obtained by the addition of local activation times to MAP duration; however, in the present study we only observed insignificant changes in local activation time in the presence of reduced [K+]o (data not shown).
By contrast, administration of tacrolimus in UN rats induced only mild but statistically insignificant changes of spermatogenesis without effects on body weight gain and testicular development or evidence of testicular injury, although the testosterone level was reduced along with elevated LH level.
Running half-year averages show significant solar cycle variations in the solar activity indices but only marginal and insignificant changes in comparison with background fluctuations for heliospheric bulk plasma and magnetic field parameters.
In particular, combined histological and DTI investigations in the mouse optic nerve following retinal ischemia demonstrated that axonal damage initially leads to decreased λ∥ but only modest or insignificant changes in λ⊥ [33].
Cadaverine (two positive charges at pH 7.0, channel in open state, o-main, Additional file 3: Figure S4A) and ornithine (one positive charge, channel in open state, o-full, Additional file 3: Figure S4B) did not produce a comparable effect on gating or open probability and only an insignificant change of the overall current (less than 5%).
Lower doses of melatonin (50 μM) produced slight but statistically insignificant changes in MAdCAM-1 expression.
