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On the basis of its important role in yeast in general control of amino acids [ 35], a quantitative characterization of the binding of Gcn4p to its promoter sites is crucial not only for elucidation of the regulatory mechanisms involved in such stress-response pathways, but also to allow design of a synthetic GCN4-induced response pathway in yeast.
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This remarkable difference in sensitivity between HIV-1 and cells to electrical stimulation could be useful not only for the elucidation of HIV control mechanisms but also for the development of novel therapies for HIV-1.
Since its discovery, siRNA has been rapidly deployed not only for the elucidation of gene function, but also for identification of drug targets and as a powerful therapeutic approach for a variety of diseases.
In this context host-pathogen systems biology can provide highly relevant clues, not only for the elucidation how the pathogen captures the host signalling mechanisms, but also for the identification of novel targets for therapeutic interventions.
Cultured cancer cells are valuable reagents not only for rapid screening of potential anticancer agents but also for elucidation of mechanism of their activity.
2D NMR spectra provide information useful not only for the structure elucidation of the molecular skeleton but also for the determination of the relative stereochemistry of the molecule and calculation of its 3-D model.
Dissolution testing in pharmacy studies the first two processes and is not only a vital tool for assessment of quality of a pharmaceutical, but also a tool for elucidation and simulation of these effects in vitro.
For elucidation of structure-function relationships only inactivating mutations which do not abolish expression of PglB are of interest.
Our mutants isolated in this study will be useful not only for an industrial application but for the elucidation of transcriptional regulation of rDNA.
Disgrace has whole passages of Wordsworth and Byron that Lurie offers to his surly students (and to us) for elucidation.
Lehman Brothers collapses, the stock market tumbles, capitalism quakes – can we turn to our bookshelves for elucidation?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com