The development of ethnically tailored therapies, however, appears irrelevant in the case of the NAT2 gene polymorphism since (1) there were only few region-specific haplotypes and (2) most genetic diversity occurred between individuals rather than between populations.
We found that only few regions replicate faster (blue), whereas many regions show significant delays in DNA replication (green).
Indeed, only few regions reached such a LOD score value by both methods in each population studied.
Ohno [35] postulated that only few regions outside of conserved syntenic region are needed for species-specific adaptation processes in evolution.
Moreover, if we varied the settings of the alignment algorithm (e.g. gap opening, gap extension, or gap distance penalties), only few regions could be recovered in identical form.
Most of the studies, however, have dealt with functional connectivity of a whole brain using simple correlation methods or effective connectivity of a local brain network with only few regions.
The identification of two, nearly identical stretches of DNA in the N. crassa genome that have not been RIPed is unexpected as previous work had identified only few regions with predicted genes that showed high similarity (Galagan et al. 2003; Smith et al. 2011).
This kind of false-positive effect may be enriched among transcripts that show correlation between blood and all brain regions, whereas correlations observed between blood and a single brain region or only few brain regions are less likely to reflect the effect of a SNP on probe hybridization affinity.
Tumours of both B20- and RAPA-treated mice, retained distinct borders and had only few necrotic regions.
Although many studies have been performed on plastid polymorphisms to evaluate taxonomy, phylogeny and phylogeography of Olea subspecies, only few polymorphic regions discriminating among the agronomically and economically important olive cultivars have been identified.
The US probe ICESat made some important measurements of ice thickness but operated intermittently in only a few regions before it stopped working completely in 2009.
