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This simple concept summarizes many biologists' informal view of gene-expression, often discussing only direction of change – up or down.
Dorsiflexion is not the only direction of movement of the metatarsal at the tarsometatarsal joint.
This is consistent with the mab-5 phenotype in QL descendants where only direction of migration is affected but not cell division, cell death, or cell fate.
In short, people in the most affluent tertiles of social or material deprivation cannot migrate to a more affluent tertile; the only direction of migration permissible (as the data are categorised) are within tertile, or downwards.
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For each of the Pre, TvN or Meta stages, consensus of gene expression was computed as the averaged mean of the bounded fold changes if studies reported values of fold changes; else, the median was computed instead if at least one study reported only directions of gene regulation.
For each study, if fold changes, θ, were reported, the standardized bounded fold changes would be |θ'| = θ/(maximum of θ) with regard to up- and down-regulated genes separately; alternatively, if only directions of up- or down-regulation were reported, the bounded fold changes would be translated into 1 for up and −1 for down, respectively.
My only direction to the both of them was, "Stir the sugar not once but six times.
These two roads are two-way, but carry only one direction of US 1 Bus./US 206.
One difference is that for our problem we need "if and only if" relationships, whereas Gusfield et al. require only one direction of the implication.
In multiple trapping experiments, only the direction of the force was determined but not its amplitude.
For decades, presidents and prime ministers, policymakers and pundits have told voters there is only one direction of travel: free trade.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com