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Indeed, proteins with a single protein-binding site can only bind to one partners at a time, underlying a simple "XOR -like combinatorial logic.
Effectors can only bind to a subset of phosphorylated binding sites, namely those that are not occupied.
This result suggests that La has a higher binding affinity to Y RNAs than Ro60, or that Ro60 may only bind to a fraction of the Y RNAs, such as misfolded ones.
Each snippet will only bind to a specific spot on the DNA molecule.
However, if the GNR is wide enough, the fullerene will only bind to the surface of GNR.
Here's how it works: DNA origami follows the basic principles of the double helix in which the molecular bases A (adenosine) only bind to T (thymine), and C (cytosine) bases only bind to G (guanine).
In the presence of NaAz, ITs cannot be internalized, they only bind to antigens on the cell surface.
HeV-specific sera effectively neutralized NiV, hence demonstrating that HeV (G-specific) antibodies not only bind to NiV G but also possess antiviral effector function.
Dr. Sadelain and Juno are working on "armored CARs" that not only bind to the target but produce immune-stimulating chemicals.
Importantly, iM10 did not only bind to the MITF coiled coil, but also to the markedly more stable HLHLZ domain of MITF.
Cardiotoxic drugs not only bind to cardiomyocyte membrane channels to block them but also modify the physicochemical property of membrane lipid bilayers in which channels are embedded.
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CEO of Professional Science Editing for Scientists @ prosciediting.com