Sentence examples for only been implicated in from inspiring English sources

Dysregulation of the mTOR pathway has not only been implicated in ADPKD, but in a number of other renal cystic disorders such as ARPKD [47] and several rodent models with mutations in other cystoprotein genes [17], [48].

Atxn2 has not only been implicated in human neurodegenerative disease, but it remains a candidate for autistic spectrum disorders and bipolar disorder due to its interaction with A2BP1/Fox-1 [39], [39].

Although the proposed fork stalling and template switching (FoSTeS) mechanism is also associated with microhomology [26], this has so far only been implicated in the formation of duplications rather than deletions, and thus FoSTeS is unlikely to have been responsible for these particular CNVs.

Other pathways, though, have only been implicated in a few cancers.

Snail has not only been implicated in EMT but also in cell survival [ 31].

Similarly, failure in establishing the Zone of Polarizing Activity (ZPA) has only been implicated in hindlimb loss in cetaceans [ 91].

We identified several genes that could only be implicated in gastrulation in specific genetic backgrounds, and not in wild-type worms.

Patients are being exposed to unnecessary blood tests, which not only is implicated in iatrogenic anaemia, but also places a significant financial burden on the department.

Therefore, peripheral and central neuroinflammation not only is implicated in the generation and maintenance of chronic inflammatory pain [ 79, 80] but also is likely to contribute to neuropathic pain [ 79, 80].

Six of the 23 genes we identified had quite low penetrance effects on gastrulation, and higher penetrance in ced-5 (n1812 ), and 13 could only be implicated in combination with ced-5 (n1812 ), suggesting that many of these genes may act redundantly or partially redundantly in gastrulation, or in separate processes that make indirect contributions to normal gastrulation.

Note that MyD88 has not only been implicated as a key player in defence mechanisms against microbial infection and inflammation, but also in several mouse tumourigenesis models.