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While only a single experiment, this provocative result suggested that growth-stimulatory fibroblasts identified in vitro might be capable of exerting both transient and more sustained tumorigenic effects on adjacent cancer cells in vivo.
Previous efforts had examined T-cell activation at one single time point [ 8, 9] or addressed costimulatory signal effects using only a single experiment [ 10, 11].
If we had performed only a single experiment at a high afterload (for example, 90 mmHg), to examine the effect of diabetes, then we would have reported that the diabetic heart has a lower value of efficiency.
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Finally, the organisation of the genetic code makes it impossible to encode functional subsets of amino acids (e.g. polar residues only) in a single experiment.
GEO and ArrayExpress' curated expression resources provide such "nearest neighbour" gene lists, but within a single experiment only, not across multiple experiments.
"The conclusion is premature and only representative of a single experiment conducted under artificial conditions," said Peter Campbell, senior environmental risk assessor at Syngenta.
Referring to CAN message interference effects, the two experiments are well comparable, because they only differ in a single experiment parameter.
The extensive experiments were performed multiple times, but only an immunoblot from a single experiment is shown.
High-throughput sequencing technologies can generate hundreds of millions of short tags (typically only 25 50 nt) from a single experiment, and this capacity is enabling a new wave of genomic research.
Either the HMECs or the HMFs expressed CFP but never both: only one cell type in a single experiment was ever CFP-positive.
Logistic limitations only allowed us to run a single experiment, which concluded to a significant reduction of bacterial counts in immunized compared to naïve mice (not shown).
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