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This will be conducted using an online randomization system.
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Eligible subjects were randomized via a central randomization system.
Random assignment was performed centrally through a validated simple randomization system version 1.2.
Patients were randomized at a ratio of 1 1 using a web-based central randomization system.
Patients were randomized 1 1 to treatment with sunitinib or capecitabine using an interactive voice randomization system.
Patients were randomized to detemir or NPH in a 2 : 1 ratio using a telephone randomization system.
Randomization in the studies was achieved using an interactive voice-response central randomization system, and numbers were not sequential within a site.
Both studies used a blinded computer-based randomization system, hence having low risk for selection bias.
Randomization will be completed using an online randomization program.
Treatment allocation was performed using online randomization generator (www.randomization.com).
The randomization key was computer-generated using an online randomization tool (www.randomization.com).
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