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There is currently a phase 1/2 clinical trial ongoing using a modified RNA oligonucleotide QR-010 that is designed for p.Phe508del mutation and is based on the 2004 publication by Zamecnik and colleagues [55].
Work is ongoing using samples from animal species (minipigs, sheep) in order to adapt the current strategy for administration in clinically relevant, orthotopic models of focal cartilage defects that provide the natural biochemical and biomechanical microenvironment for chondrogenesis (Cucchiarini et al. 2005; Ivkovic et al. 2010; Pascher et al. 2004).
Experiments are ongoing using higher cumulated dosages of anti-GITRL antibody to improve the effect (i.e. complete protection from diabetes development).
These arguments are not without merit and promising clinical studies are ongoing using allogeneic cells or tissues to treat a variety of neurological indications.
The analysis is ongoing using the noncompartment model.
To date, few investigations are ongoing using this technique in clinical oncology [ 29, 30].
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There are also reports of anti-US placards in Tahrir Square challenging CNN's ongoing use of the c-word.
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"I believe the trial effectively rules out the value in ongoing use of creatine, at least at that dose," Dr. Rothstein said in a statement.
Unlike carbon credits, where companies essentially pay to offset their ongoing use of dirty energy, renewable PPAs genuinely result in a switch to the clean stuff.
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