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Since our initial analysis compared all action potentials generated during the UP state, we wondered whether the effect of thalamic stimulation during ongoing UP states could have a temporal signature that could be missed by our analysis.
We explored the temporal dependency of the effect of thalamic stimulation on cortical UP states by generating peri-stimulus time histograms of action potentials generated during ongoing UP states, centered on the time of the thalamic stimulus onset (Figure S3).
Using patch clamp recordings of connected cortical neurons we also found that corticocortical synaptic inputs were depressed during ongoing UP states, indicating a failure of the signal to propagate through the circuit, beyond these few responsive cells (see also Figure S4d).
Although infection control and safety measures have improved steadily since the discovery of the epidemic, the totality of the evidence suggests also that appreciable HCV transmission is likely ongoing up to the present.
It depends on what caused the infection and whether the cases can be tracked back to one day, or if transmission was ongoing up until the day the farm was closed".
The manual search and personal author contact will be ongoing up to the end of the data collection phase.
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It's an ongoing up-skilling of our coaches, our players, our culture, because Andy has shown just how much hard work is needed to get there.
In the introduction, however, there are already three references to the ongoing up-rise of alternate views advocating the potential importance of sympatric speciation (Via, 2001, Nosil et al. 2005, Mallet et al. 2009), and the paper by Dieckmann and Doebeli is duly referenced in two of those more recent publications.
Similar to the results obtained with ongoing spontaneous UP states, we found that there was no prolongation, nor increases in amplitude or spike rate, during stimulation of ongoing thalamically-triggered UP states (Figure 5e and 5f).
Health teaching and prescriptions were delivered on the spot with ongoing follow up and counselling support.
BHOMA intervention began in Aug 2010 in six pilot primary health facilities, and Apr 2011 in 40 primary health facilities, with current ongoing follow up.
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