Thus, a better knowledge of the molecular mechanisms and cellular targets of CQ or HCQ should be considered in the ongoing clinical trials where CQ or HCQ are used as autophagy inhibitors.
The current reports indicate that CQ or HCQ is often used in combination with chemotherapeutic drugs to enhance the efficacy of tumor cell killing; however, its sensitizing effects can also occur independently of autophagy inhibition, which should be considered in the ongoing clinical trials where CQ or HCQ are used in the treatment of breast cancer.
Inge Marie Svane (Herlev Hospital, Denmark) presented data from an ongoing phase I/II trial where TILs were infused in combination with IL-2 in low (2 MIU/day, sc. for 14 days) or intermediate ("decrescendo-regimen", 18 MU/m over 6, 12, 18 and 24 h, followed by 4.5 MU/m/day for 3 days) doses.
These continuing political attacks are baseless and unprecedented and take the focus away from where it belongs — the ongoing trial in Seattle".
Subjects were aware that they could be tripped on either leg, but did not know whether and where an obstacle would appear in the ongoing trial.
The optimal way of doing this is to conduct nested trials of recruitment interventions in ongoing randomised clinical trials, where some patients in the trial are randomly assigned to an ethnically sensitive method of recruitment, and some receive a standard model.
One publication reported on an ongoing trial [49].
It's an ongoing trial so I've got to be very careful, there's a limit to what I can say, but I just don't fully understand how we got to where we are.
He's in the middle of an ongoing trial, I'm in the middle of an ongoing trial, but he's a strong kid.
The search of the ongoing trial registers did not reveal any ongoing trials.
