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The majority of patients in this study were in an early stage of disease at presentation, possibly due to ongoing sensitization programmes and an increase in the number of hospitals that provide free cancer treatment in the Lake zone regions in recent years, compared to the past treatment modalities for NHL cases [ 2, 9- 11].
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It could speak to the success of prior and ongoing GBV sensitization campaigns about rape.
Last but not least, a soap distribution is organized every month in parallel to the ongoing hygiene sensitization campaigns.
The major synaptic alteration that contributes to central sensitization and ongoing pain is when increased activity in one set of synapses results in the facilitation of the activity in another set of synapses [34].
The major synaptic alteration that contributes to central sensitization and ongoing pain is when increased activity in one set of synapses results in the facilitation of the activity in another set of synapses [ 34].
Interestingly, in the MIA-treated animals, secondary mechanical hyperalgesia developed from day 3 on and lasted for at least 14 days compared to secondary tactile allodynia, which was more pronounced during the early phase of arthritis development, reflecting an ongoing development of pain sensitization based on different molecular mechanisms during the 14 days after MIA treatment.
Ongoing researches demonstrated that central sensitization could reach critical clinical implications for chronic head and neck pain [8].
The resulting DLPFC dysfunction contributes to central sensitization and subsequent ongoing and exaggerated pain, and also decreases the patient's ability to disengage from the pain, thus feeding back into the negative psychological influences.
Although the debate regarding the pathophysiology is still ongoing, the role of excessive regional inflammation, peripheral sensitization of primary somatosensory afferents, and central sensitization of spinal neurons is becoming clear [ 1, 2, 12, 13].
The ongoing migraine imaging study will compare central sensitization in the interictal vs. migraine attack state in a within-subject design.
The induction of a TH2/TH17-skewed cytokine environment in the lung may directly drive asthmatic symptoms, as well as lead to the sensitization to or enhancement of ongoing immune responses to heterologous antigens in susceptible individuals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com