Sentence examples for ongoing selection pressure from inspiring English sources

Moreover, growing evidence of viral escape within CD8+ T cell epitopes during acute and chronic SIV or HIV-1 infection demonstrate that CD8+ T cells can exert strong immune selection pressure on the virus [8] [10], [11], [12], [13], although the evidence for ongoing selection pressure in chronic infection is less clear-cut [14].

The strong 'footprint' associated with this epitope in this study is important and may indicate ongoing selection pressure at some level.

Our observation of a depletion despite the fact that CRISPR/Cas systems are dynamic and often occur in labile genomic regions, is surprising, because an ongoing selection pressure is needed for this observation.

28 Furthermore, these mutations tend to become fixed within the circulating quasispecies, perhaps reflecting ongoing selection pressure in the liver. 2 Although we have not looked for T cell responses in longitudinal studies across other populations, several studies have looked for the presence of HLA-associated footprints in diverse populations.

Not only do overlapping genes preserve features relating to their mutational origin, but secondary features relating to ongoing selection pressures.

In this way and as indicated by the selection analyses performed [ 75], there is ongoing selective pressure on certain RHDV strains, and consequently the fixation of favourable mutations or the purging of deleterious variants would result in the strong decrease in the relative genetic diversity recently observed for the virus [ 76, 77].

We have also detected weak evidence for ongoing selective pressure in the human genome on the STK11 and CDH1, but these signals of selection may be artifacts of the very small effective population size of modern humans.

Natural communities of species reflect the sum of these species' interactions and the ongoing complex selection pressures they constantly endure that drive their evolution.

The data are consistent with already existing adaptive divergence between the groups and they also strongly indicate potential for rapid response to ongoing changes in selection pressures.

In L. delbrueckii subsp. bulgaricus, the changes in GC3 are attributed to ongoing evolution [ 11], and similar selection pressure might be responsible here.

Moreover, ongoing growth in the presence of hygromycin gives selection pressure for cells that do not harbour Cre recombinase as this will permit the stable retention and expression of the hygromycin resistance gene.