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However, adjacent to the bone marrow there was an endosteal callus with very little necrotic bone, but instead a dense remodeled bone with an irregular osteonal structure and vivid ongoing remodeling.
Moreover, both histological and immunohistochemical evaluations showed type II coll in the cartilage region down to the subchondral bone, and the uniform presence of type I coll in the subchondral layer, even if aspects of ongoing remodeling were still present at 6 months (Kon et al. [2010a]).
The pathogenesis of pulmonary fibrosis is thought to result in part from repeated bouts of injury leading to ongoing remodeling responses and dysregulated repair.
Note also the underlying area rich in growing vessels (Fig. 7B, b2, dashed arrows) with small, narrow lumina and very close to each other, suggestive of an ongoing remodeling process.
This ongoing remodeling of the brain is the dynamic context in which undergraduate educational experiences are both impacted by and contribute to the development of higher-order cognitive processes and evaluative thinking.
Experimental animal studies indicate that there might be an early window for intervention to tune the immunological response to cardiac injury limiting infarct expansion and induction of ongoing remodeling in the remote myocardium.
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The data thus supports the idea that elevated levels plasma levels of MMP-9 before onset of disease may reflect an ongoing remodelling and early pathogenesis of the arterial wall and/or a low-grade systemic inflammation.
The subchondral tissue included discrete areas that were positive for type II collagen; the hypertrophic chondrocyte morphology suggested ongoing remodelling towards a bone matrix.
The progesterone receptor (PR) interacts with chromatin in a highly dynamic manner that requires ongoing chromatin remodeling, interaction with chaparones and activity of the proteasome.
For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling.
Altogether, activation of these pathways indicates ongoing tissue remodeling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com