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Twenty-six patients (35%) had active disease immediately prior to allo-SCT; only three were alive at time of analysis (12%) including one with ongoing relapse.
Ongoing plans for prevention of relapse, or risk intervention, may be needed; future research may be able to identify those in need of ongoing relapse risk monitoring and intervention.
A trial is currently underway that will assess the anti-HER2 therapy lapatinib in response to the chronic high and ongoing relapse risk for this subtype of the disease [ 15].
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Although new treatments based on immunomodulatory drugs and proteasome inhibitors have prolonged life-expectancy, the prognosis is still typically a sequence of ongoing relapses.
Secondly, it is yet unknown whether global RNFL reduction (apart from RNFL changes due to ON) really exists in all MS patients, and if so, when RNFL reduction may occur and whether it arises from continuously ongoing or relapsing (remitting) axonal changes.
By way of illustration from our own data, at 5 years follow-up, a relapse-free patient with an ER-negative tumour will have a lower ongoing HR for relapse and death than a patient with an ER-positive cancer.
How should addicts and their loved ones best handle the ongoing risk of relapse?
The narrative at 3 months described mortal illness in ICU (Being at Death's door), the narrative at 5 months described ongoing fear of relapse (Still not out of the Woods), and the narrative at 10 months had three potential outcomes: downhill (detour on the road), steady-state (end of the road), or progress (The Road to Recovery).
Despite the promise of a graft-versus-myeloma effect, the major current shortcoming of allogeneic transplantation in MM is the ongoing risk of relapse.
More recently implementation intentions have been shown to facilitate ongoing goal striving (relapse prevention), protecting individuals from the influence of potentially disruptive inner states such as cravings [ 24].
Postmenopausal women with early breast cancer are at an ongoing risk of relapse, even after successful surgery and treatment of the primary tumor.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com