Patients with vascular events within 6 months were excluded, as were patients with QTc prolongation (>470 ms) and ongoing cardiac dysrhythmias.
Similar to the results obtained with ongoing spontaneous UP states, we found that there was no prolongation, nor increases in amplitude or spike rate, during stimulation of ongoing thalamically-triggered UP states (Figure 5e and 5f).
Among them, 497 patients had only an "entry" document followed by several "prolongation" documents because their treatment episode was still ongoing at the end of the study period.
The ongoing conflict between the leaders of the Awami League and the BNP is a prolongation of the three-decade hostility between these two families.
Many challenges to its implementation as a safe and viable therapy for brain tumours still need to be addressed; nevertheless, results from ongoing Phase I/II clinical trials are encouraging, as disease stabilisation and patient survival prolongation have been observed.
Prolongation of the QT interval and risk of torsades de pointes (TdP) are ongoing issues for both the pharmaceutical industry in drug development and for clinicians assessing patients following drug interactions or drug overdose.
The phase 3 study showed a 48% reduction in the mean annual incidence of SRE (P = 0.005), 5 months prolongation in the median time to first SRE (P = 0.009) and 36% reduction in the ongoing risk of SREs at 24 months [6,7].
Ravenel, M. P., The Gordon Bell Memorial Lecture, 1925, on "The Prolongation of Life.
Survival prolongation only occurs when degradation of p62 is restored.
The method uses a nonlinear prolongation operator.
The memos emphasized a potential risk called QT prolongation, in which the heart delays recharging electrically.
