Exact(5)
Spinal manipulation for treating an ongoing migraine headache is not supported by evidence.
The ongoing migraine imaging study will compare central sensitization in the interictal vs. migraine attack state in a within-subject design.
Unlike previous studies of functional brainstem abnormalities in migraine, this study was able to directly compare migraine patients with healthy subjects due to the absence of ongoing migraine pain.
In summary, there was an ineffective release of endogenous μ-opioids acting on μOR in the right mPFC to fight the ongoing migraine pain.
It may be postulated that trigger factors that have been identified by migraineurs are much less common than generally assumed and may simply reflect premonitory symptoms during the early phase of an already ongoing migraine attack.
Similar(55)
Firstly, for those women with pre-pregnancy migraines, ongoing complications of pregnancy such as vascular diseases may have led to a flare-up of migraine headaches as a result of the stress of being ill.
There is an ongoing debate regarding whether migraine pain originates in the perivascular nerves, in the CNS or both [10, 36].
Currently, there is an ongoing PAC1 receptor antibody trial for migraine treatment (ClinicalTrials.gov Identifier: NCT03238781).
There is an ongoing discussion about whether patients with migraine are at decreased risk of developing breast cancer [16] based on the involvement of hormonal factors in migraine and breast cancer.
Further, large international collaborations are ongoing aiming at combining genome-wide genetic data on migraine to increase the power to identify additional genetic variants in migraine.
The underlying mechanisms of the prophylactic efficacy of substances used in migraine prevention are a matter of ongoing discussion.
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