Exact(13)
Starting from a critique of current dominant models of computation, and drawing on the philosophical notions of the virtual and the event, uncertainty, contingency and indeterminacy are proposed as virtualities that express the ongoing differentiation of digital matter.
CD27 expression indicates ongoing differentiation but is missing in Z138, whereas SUDHL4 expresses CD27 confirming the memory B-cell state of these cells.
Our analysis of non-melanoma skin cancers show that BCC are negative, but the majority of SCCs have relatively high levels of C/EBPδ, especially in areas of ongoing differentiation.
Indeed, ongoing differentiation is a routine feature of EpiSC cultures.
Besides from dedifferentiation of existing cardiomyocytes, another possibility is an ongoing differentiation of progenitor cells within the HDS to new cardiomyocytes that start expressing α-sarcomeric actin.
Studying ongoing differentiation processes in small-scale situations with unlimited dispersal opportunities is therefore crucial to investigate the mechanisms driving adaptive divergence.
Similar(47)
We next analyzed the effects of MYC on the expression of NeuroM, a marker of ongoing neuronal differentiation, that specifically localizes to the intermediate differentiation zone (IZ) of the developing neural tube [ 21].
Hepatic acini/plates of CK18 + cells expressed hepatocyte nuclear factor 4-α and β-catenin, indicating ongoing hepatic differentiation.
However, it proved very difficult to conclusively distinguish secondary introgression from ongoing parapatric differentiation.
This mechanism may contribute to ongoing ecotypic differentiation and ultimately speciation [5], [6], explaining why fixed chromosomal inversion differences often distinguish closely related species [4].
Secondary introgression can be difficult to separate from ongoing primary differentiation with gene flow (i.e. parapatry), because the high stochasticity of the coalescence process often leads to a full range of situations, from reciprocal monophyly to extensive allele sharing [6].
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