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Furthermore, although slowing ongoing deposition or clearing pre-existing deposits in preclinical stages of AD might be predicted to have some clinical benefit, there is a reasonable possibility that Aβ aggregates trigger downstream events that contribute to neurodegeneration that subsequently becomes self-sustaining.
Burial can occur in response either to ongoing deposition of sediments above the sample or tectonic loading brought about, for example, by thrust-faulting or large-scale folding of the region.
Ongoing deposition was collected on float Planilux® 6 × 6 × 0.2 cm glasses were displayed in the showcase for five and a half months, both horizontally and vertically.
One can see that with ongoing deposition, the concentration of silver increases, while the fluorine content decreases and becomes undetectable on the sample sputtered for 200 s.
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A geyser's eruptive activity may change or cease due to ongoing mineral deposition within the geyser plumbing, exchange of functions with nearby hot springs, earthquake influences, and human intervention.
Moreover, the enclosure of copper during cyclic electrodeposition is promoted by three properties of the process (see Figure 1): first, negative current densities are observed during the anodic scan in the copper dissolution range (>0.10 V vs. SCE) in the Pt-only-electrolyte indicating an ongoing platinum deposition.
In particular, the concentration of Aβ1 42 in the CSF undergoes a characteristic drop during disease progression, which is interpreted as the consequence of the ongoing parenchymal Aβ deposition in senile plaques.
Since the solubility of urate in physiologic solutions is exceeded at approximately 6.7 to 7.0 mg/dL, current guidelines for inhibiting ongoing urate crystal deposition, reduction of total body urate stores, and resolution of macroscopic tophi are for continuing (lifelong) reduction of serum urate concentration to <6 mg/dL (approximately 360 mmol/l), and ideally in the 5 to 6 mg/dL range [ 18].
Thus, in the presence of ongoing complement activation, the deposition of serum IgA1 antibodies enabled the co-deposited IgG1 antibodies to better maintain their ability to interact with antigens.
Roughly 15% of circulating lead per day is incorporated into bone (Rabinowitz et al. 1976), where it substitutes for calcium in the hydroxyapatite of bone mineral during the normal and ongoing process of bone deposition.
Accordingly, post mitotic cells, such as cerebral cortical neurons, accumulate high levels of nucleosomal H3.3 (87 % of nucleosomal H3 content) as DNA synthesis-independent H3.3 deposition is ongoing while replication-coupled 3.1 and 3.2 deposition stops during gestation (Pina and Suau 1987).
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