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We wheeled him in for a computed tomography (CT) scan to find out if there was ongoing bleeding.
Ongoing bleeding and reasonable expectation of benefit are mandatory even for compassionate off-label use of rFVIIa.
In accordance with protocol inclusion criteria, all patients were hemodynamically unstable (6 units of RBCs within 4 hours of admission and ongoing bleeding as determined by the investigator).
BLEED criteria = ongoing bleeding, low systolic blood pressure, elevated prothrombin time, erratic mental status, unstable comorbid disease; GIH = gastrointestinal hemorrhage; ICU = intensive care unit.
Ongoing bleeding may obscure the endoscopic field, prolonging the procedure and reducing safety and accuracy.
This protocol is used even when there is no clinical indication of ongoing bleeding.
The transfusion of platelets is the initial treatment for ongoing bleeding after adequate heparin neutralization in many institutions [3, 6].
CT scan is easily and quickly performed and provides useful information such as the localization, evidences for an ongoing bleeding or compression on adjacent structures.
Arterial-phase acquisition completed with maximum-intensity projection (MIP) reconstructions at vascular window settings may effectively show active contrast extravasation in the duodenum, indicating ongoing bleeding (Fig. 9).
These devices create a tamponade effect against ongoing bleeding by reducing the intrapelvic volume and also restore stability, bone contact and favour blood clotting.
Acute interventions that minimize or arrest ongoing bleeding and hematoma size are likely to be critical for improving outcomes [4, 13].
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