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To understand the ancestral mechanism of vessel formation, we investigated the invertebrate cephalochordate amphioxus and compared its developing vessels with the homologous ones in mouse (Fig. 5).
Therefore, in order to understand the ancestral and conserved part of cardiovascular tube formation, we investigated developing vessels in the invertebrate amphioxus and compared these vessels with the homologous ones in mouse.
In our previous study streptozotocin-induced diabetes decreased the mRNA levels of several proangiogenic proteins and increased those of antiangiogenic ones in mouse skeletal muscle [ 4].
Using the program K-Factor [ 39], we detected two 6 bp motifs with a significant enrichment (K-Factor score ≥ 3.5) in the regions 1000 bp upstream of the transcriptional start site in human imprinted genes (tgcgta and gcgtat) and seven different ones in mouse imprinted genes (atagcg, atcgca, cgtacg, ctacga, tgcgtg, tgtcga, ttggcg).
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The in vivo results of the fluorescent image indicated that TGL possessed an effective BBB penetration than that of unmodified ones in mice.
However, the numbers of corresponding proteases vary from ten KLKs in cows, eleven in dogs, and 26 ones in mice.
I analyzed 1598 genes with two co-orthologs in zebrafish, but only one in mouse.
The XC subfamily of chemokines contains two members in human but only one in mouse.
We first compared our regional results to two previous studies of hippocampus - one in mouse [ 29] and one in human [ 31].
The genes have one ortholog in worm (F08F8. 2) and one in mouse (HMG-CoAR, MGI96159) which both have embryonic lethal KO/KD phenotypes.
It includes eight sno-lncRNAs in human ESCs, three in ENCODE human cell lines, seven in rhesus ESCs and one in mouse ESCs.
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