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We also looked at the carrier frequency of these variants in ESP6500 database and considered the frequently reported ones as predicted 'non-pathogenic'.
As the mutated residues are the same ones as predicted to be involved in coiled-coil formation in the STIL oligomer, it is likely that STIL-CC/PLK4-PB3 binding and the STIL self-interaction are coupled and not independent events.
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The analysis identified three clearly conserved regions, one covering exon 1 as predicted, but another was found in the immediate 5' region and one other in intron 1.
The Standard Model predicts a slight bias in these probabilities, and after a mere 90 million trials, the team found it: left-spinning electrons were 0.0000175% more likely to richochet than right-spinning ones, just as predicted.
For males, symmetric Hadza (χ2 = 2.9, p = .088, p = .044 one-tailed as predicted from measurement data), macaques (χ2 = 3.9, p = .048), and Europeans (χ2 = 8.0, p = .005) were selected as more typically male than asymmetric Hadza, macaques, and Europeans.
It is generally admitted that plant tissues are more valuable, and herbivory more impactful, at the early stages of development [ 10], and thus that young plant tissues (e.g. seedlings and saplings for herbaceous plants, young expanding leaves for trees) should be more protected than older ones [ 11], as predicted by the optimal defense hypothesis [ 12, 13].
She wrote: "So one year later, as predicted, a new dialogue emerged.
Approximately half of the proteins (again including all vertebrate ones) had signal peptides as predicted by the SignalP algorithm[ 40].
The four 6-fluoro-8-methoxy-quinolones are active on T. gondii but only one is as active as predicted.
Further, it was observed that 22 SNPs created one or more new transcription factor binding sites (TFBS) while 25 SNPs completely lost one or more TFBS as predicted by Genomatrix ElDorado program (data not shown).
With refinements, by the mid-1970's, the experiment started counting solar neutrinos, but only one-third as many as predicted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com