Later, platinum-ruthenium (PtRu) is introduced to increase the reaction rate, but the kinetic parameter of the catalyst is still the one of a major problem in DMFC.
When NER encounters two closely spaced lesions, one on each strand, a major problem arises.
Individual differences among patients and even in different areas of the same tumor in one patient may cause a major problem with PDT: dose calculation during application of the light.
Being victimized by one's peers is a major problem in adolescence, and research has suggested that individuals with autism spectrum disorders (ASD) may experience higher rates of bullying than their typically-developing (TD) peers.
"Chugging one beer is not a major problem," said Watson.
One area identified as a major problem for farm communities is alcohol misuse and its associated problems - preliminary research suggests that 54 per cent of men and 22percentnt of women in the broad acre agriculture industry engage in high risk drinking at least monthly [ 3, 4] based on the National Health and Medical Research Council (NHMRC) 2001 guidelines [ 5].
American poetry criticism faces a major problem, one that has nothing to do with poetry, or readers, or anything remotely literary.
Entitled "Still Loony," the chapter is an extreme instance that typifies a major problem, one that worsens as the book proceeds: because he wants to get everything in, including hundreds of dropped names, Townshend can't take the time to make much come alive.
An airspeed sensor on the plane had iced over and stopped functioning – not a major problem, but one that required the pilots to take control.
Air pollution is a major problem and one of its impacts is on health.
The monarchy has a large advisory board, and there was a major problem with one king dead and the man-who-would-be-king a murderer.
