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The intervention will start within one week from baseline measurements, health guidance and the randomization.
Follow-up after one week from baseline will be conducted in the ICG only (Table 2).
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The primary endpoint of both trials was defined as both three or more CSBMs per week and an increase of at least one CSBM per week from baseline for at least 75% of the weeks of the treatment period.
Patients are also asked to bring a sample of their drinking water from home on two separate days during one week at baseline and month 6.
After one week of baseline BP recording, male and female SHR were randomized to receive the selective COX-2 inhibitor celecoxib (10 mg/kg/day) or vehicle for six weeks (from 9 to 14 weeks of age).
Measurements of cognitive decline are applied one week before baseline and at week 11 and week 21 after baseline.
Sessions commence within one week of baseline assessment.
Training will commence within one week of baseline assessment.
The exercise program will last 12 weeks and will start within one week of baseline testing.
For the physical activity group compared with the control group, there was a 40%95%5% confidence interval 13%to73%34), 34% (6%to69%9%), and 46%12%to91% 91%) greater increase in self reported minutes carrying out physical activity per week from baseline to one week, four weeks, and six weeks post-quit day, respectively.
After a one week baseline, the patient received three treatment sessions over a ten day period.
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