In fact, one synapse may contain on the order of 1,000 molecular-scale switches.
The names of synapses on protrusions with more than one synapse (e.g., branched or multisynaptic spines) were further appended with 'a', 'b', 'c', etc. Traces made outside of the reconstructed volume were given the suffix '_o' for 'outside'outside
The spread of a seizure relies on high-frequency firing of synapses, which leads one synapse to activate another, cascading throughout the brain's circuitry.
If I had asked you out of the blue, "Guess who's back for the Super Bowl advertising this year," you'd probably say without giving one synapse time to fire, "The Budweiser Clydesdales". Tension?
Five synapses were made along ax024 (7.9 μm) in this volume while the other two (ax118, 5.3 μm and ax047, 6.0 μm) made only one synapse each.
(h) Object 4 was identified as ax018, which formed one synapse (d010c16Ax018e) in the reconstructed volume with dendrite 10 (d010).
In part, because they are tagged by these immune proteins, yes — but what marks one synapse for elimination and not another?
(g) Object 3 from section 118 was found to be part of ax148, which made one synapse in the reconstructed volume with a nonspiny dendritic segment (d005, orange) that had 12 asymmetric, presumably excitatory synapses (red) and one symmetric, presumably inhibitory synapse (blue) along its length.
Our analysis progressed through a network of two neurons with static synapses, the same network but with one synapse having plasticity and finally with both synapses showing plasticity.
Fig. 5 Two-cell network with synaptic plasticity in one synapse.
