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Employing functional measures of HR pathway deficiency rather than relying on documented changes in specific genes should capture more patients who might benefit from DNA-damaging therapies, and Vollebergh and colleagues should be congratulated on developing one such assay.
One such assay, based on one tetra-allelic and a number of tri-allelic SNPs has just been developed using this information [ 31].
One such assay is based on monitoring p53 and p21 accumulation after cell exposure to etoposide and nutlin-3a enabling the differentiation of TP53 and ATM defects using flow cytometry.
One such assay GeneXpert® has recently been released.
One such assay, using a reporter gene that marks a telomeric tract, has been described above (Dunham et al., 2000).
One such assay, the ARCHITEC T® HIV Ag/Ab Combo Assay(ARCHITECT), has recently been approved by the Food and Drug Administration FDAA) for use in the United States.
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In this study, the primers and probe of one such published assay, are examined for their ability to quantify different genotypes of parvovirus B19.
We have developed one such functional-based assay that we are utilizing to identify potentially hundreds of molecules that can alter specific cell-fate responses.
One such approach, blood-based assays, offers distinct advantages.
The bimolecular fluorescence complementation (BiFC) assay is one such novel method for which tools and protocols for its application in plant cell research are still being developed.
One such bioassay is the uterotrophic assay, designed to evaluate both ER agonists and antagonists.
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